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It also upregulates antioxidant enzymes including superoxide dismutase (SOD) and catalase

Superoxide dismutase (SOD) activity was quantified using a commercial kit, based on the inhibition of WST-1 formazan dye generation

For example, increased levels of the Egr gene were observed at 1 h, Nos , Srf , and Kras genes demonstrated increased expression at 1 and 24 h in all vessels, and Egr expression was increased at 24 h in both ovarian veins

But scientists quickly realized its effects were far from localized

FDA concluded in 2026 that evidence was insufficient to support wound-healing effectiveness