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It leads to stress-eating, skipped doctor visits, and avoidance of movement

Monitoring for gallbladder issues is important during rapid weight loss

The Phase 3 SYNCHRONIZE trials incorporate slower dose titration with the option to pause dosing during more severe symptoms, which should improve tolerability

The theory behind microdosing is that a smaller dose still activates those pathways enough to see benefits, without triggering the aggressive nausea, fatigue, and hair thinning that higher doses can cause

The first to file in the US gets a 180-day period of exclusivity during which it can be the sole marketer of the generic version

ClinicalTrials.gov: TRIUMPH program registry entries