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Diabetes Care 2005;28:89-94

Summary After decades of speculation, therapeutic interventions that target the intestinal barrier are nearly within reach

Aberrant one-carbon metabolism processes have been associated with raised homocysteine levels as well as neural tube defects (NTDs), mood disorders and chronic diseases of lifestyle including certain cancers, and cardiovascular disease (CVD)

This is not a quality defect, but a typical property and a sign of the absolute purity and authenticity of the raw material.

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KG-dependent carnitine synthesis via TMLHE increases histone acetylation Carnitine is needed to transport some acyl-groups across the inner mitochondrial membrane, and acylcarnitines are known to be important for both energy production and redox balance (Flanagan et al., 2010