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doi:10.1016/j.soard.2013.04.017

However, if you experience any persistent or severe reactions, such as swelling, difficulty breathing, or other concerning symptoms, its important to contact your healthcare provider immediately

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[31] The products are usually extracted and purified by phenol-methylene chloride extraction or by column chromatography

Requires Daily Dosing: Oral supplements often need to be taken daily, as the body absorbs smaller amounts at a time