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This oxidative stress triggers lipid peroxidation, the hallmark of ferroptosis

12 Potential adverse effects and risk considerations of probiotic supplementation 12.1 Historical safety record and regulatory frameworks For centuries, the consumption of fermented foods containing live microorganisms has been associated with human health benefits, providing a strong historical foundation for their safety

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Because it is not renally filtered as an intact molecule in the same way small organic drugs are, its renal contribution is considered indirect, though the full elimination profile in humans has not been formally characterized