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The TRIUMPH trial program includes over 2,000 participants and is expected to complete in 2026

Interestingly, when patients started with a lower dose of 2 mg instead of 4 mg, the intensity of these side effects was reduced

GLP-1 Activity GLP-1 receptor activation can help reduce appetite, slow gastric emptying, support insulin response, and improve blood sugar regulation

The company is also testing retatrutide in adults with obesity or overweight and type 2 diabetes, as well as adults with obesity or overweight and heart disease

How should Retatrutide be stored in laboratory environments

Typical trial exclusion criteria for retatrutide studies, consistent with those applied to similar investigational and licensed medicines in this class, have included: pregnancy or breastfeeding (with active contraception requirements during participation)