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Intestinal OCT1 transport and GI intolerance with metformin Given the role of OCT1 in potentially altering local concentrations of metformin, our group (Dujic et al) proposed that a reduction in function of OCT1 might alter the risk of GI intolerance in patients treated with metformin [7]
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These therapies interact with natural pathways involved in appetite and glucose balance, and are prescribed following a medical evaluation
More in hormones HRT Black Box Warning Removed: What the FDA's 2025 Decision Means The FDA moved to revise the HRT black box warning in 2025
10.1155/2021/7689045 21 ChaudharyN.ChoudharyB.ShahS.KhapareN.DwivediN.GaikwadA.et al (2021)
Udomsinprasert R, Pongjaroenkit S, Wongsantichon J, Oakley AJ, Prapanthadara LA, Wilce MC
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