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The inflection point arrives in 2029-2030, when Mounjaro surges to $36 billion while Keytruda drops to $17 billion due to biosimilar competition and IRA pricing pressures

This can be due to reduced calorie intake, changes in metabolism, or mild dehydration from side effects like nausea

Although the specific role of B cells in gastrointestinal immunity remains unclear, they secrete immunoglobulins (eg, IgG, IgA) that participate in local immune responses

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