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The GSSG-dependent oxidation of roGFP2 by fused PfGrx variants is two to three orders of magnitude faster than the oxidation by unfused PfGrx(SSG) variants and more than seven orders of magnitude faster than the uncatalyzed reaction with GSSG (Table 1)
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Indeed, some CVDs (such as myocarditis, dilated cardiomyopathy, or aortic aneurysm) have seen little investigation into ferroptotic mechanisms [380]
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