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Overall, while these technologies hold promise, some research underscores that none have fully resolved the combined challenges of degradation, absorption, and metabolic clearance in humans

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Comment: In response to our concern that the LithoVue TM Elite Ureteroscope may be appropriately described by C1747, the applicant stated that while C1747 does describe a single-use ureteroscope, the descriptor is too broad and does not include the key featureIRP monitoringthat makes the LithoVue TM Elite Ureteroscope unique