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Slices were anchored in a glass-bottom chamber using a harp (Warner instruments) and imaged using a 40 water immersion objective
In lupus, SOCS1 function is often impaired, contributing to the uncontrolled immune activation that characterizes the disease
This multi-target mechanism explains why it has documented effects on skin, hair, wounds, lungs, and even cancer gene regulation something that would be puzzling if it only had one mechanism
Together they leave almost no tissue type behind
Everything from our hair, nails, eyesight, and even genitals will be affected with age
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