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Figures 6AD, DSS-induced mice exhibited significantly increased SIRT1 expression and decreased p-STAT3 expression compared to the Control group

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It is important to note that while Zepbound itself has been available since November 2023, the active ingredient tirzepatide was previously approved under the brand name Mounjaro for type 2 diabetes management in May 2022

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[DOI] [PubMed] [Google Scholar] 27.Evans AM, Fornasini G