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Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour

Gastrointestinal symptoms that some patients experience during treatment (such as nausea, vomiting, or altered bowel habits) typically improve within two to three weeks of discontinuation, though the extended half-life means these effects may persist longer than with shorter-acting medications

Both responses are real, and neither is unusual

Medical supervision remains constant throughout treatment, with healthcare providers regularly evaluating patient progress and adjusting doses as needed

J Obes Metab Syndr 2021;30:129

In the brain, creatine also acts as an energy source