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Building on these findings and the teams previous research on glucagon-like peptide-1 receptor agonists (GLP-1RA) effect on cerebrovascular protection, they conducted the worlds first randomised clinical trial to evaluate GLP-1RAs in patients undergoing reperfusion therapy for severe ischaemic stroke caused by large vessel occlusion (LVO)

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Research in rats shows that the peptide substantially increases the rate of collateral blood vessel growth in the setting of ischemia [4]

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