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It's been studied in monkeys and rabbits and all of that information was extrapolated to humans

51 Obstructive sleep apnoea In a one-year study of adults with moderate to severe obstructive sleep apnoea and obesity about half of whom were treated with positive airway pressure at baseline tirzepatide 10 or 15 mg once weekly resulted in a clinically meaningful reduction in the apnoeahypopnoea index compared with placebo

12 It comprises of three subtypes, CPTIA, CPTIB and CPTIC, which show tissue-specific distribution