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Furthermore, pharmacokinetic heterogeneity across patient populations, driven by genetic polymorphisms in metabolic enzymes or variable tumor microenvironment conditions, necessitates personalized dosing strategies yet remains underexplored in clinical settings [164]

According to Statistics Canada, approximately 27% of Canadian adults live with obesity, while an additional 36% are classified as overweight

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doi: 10.1016/j.cbpa.2017.02.020

IGF-1 is one of the primary activating signals for satellite cells, and understanding how sustained IGF1R activation affects satellite cell proliferation, differentiation, and fusion is a key question in muscle biology