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GLP-1 medications like Ozempic, Wegovy, Mounjaro, and Zepbound have become powerful tools for treating type 2 diabetes and obesity

And we do not know whether the migraine benefit is specific to people with obesity or extends to normal-weight migraineurs

You could think of semaglutide as a key that unlocks one lock, tirzepatide as a key that unlocks two locks, and then reta unlocks three locks, says Wajahat Mehal, M.D., director of Yale Weight Loss Program

[9] [10] [14] [7] This is especially important because a good experience on GLP-1 or GIP therapy can suddenly turn confusing if your thyroid dosing is no longer aligned with your body

The choice may ultimately come down to availability, given that tirzepatide is currently the only FDA-approved option

We asked our experts for the best options, and how to use them