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Rekdal VM, Bess EN, Bisanz JE, Turnbaugh PJ, Balskus EP

Discussion Here we investigated the contribution of the TSS pathway to the antioxidant and ferroptosis stress regulation in SCD erythroblasts

The glutathione S-transferase (GST) superfamily comprises several independent members, including the omega ( Gsto1 and Gsto2 ) and the mu ( Gstm1 and Gstm2 ) families

Mechanistically, a microglial inflammation-oxidative stress feedforward loop perpetuates injury: Activated microglia secrete neurotoxins, impairing neuronal mitochondrial function and antioxidant capacity (such as GPX4), thus increasing ROS leakage

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Methylation is a biochemical process that happens billions of times every second, affecting everything from DNA repair to energy production