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Hereditary hemochromatosis, characterized by a recessive mutation in the hemochromatosis (Hfe) gene, has been shown to elevate malondialdehyde (MDA) levels in colonic tissues of Hfe gene knockout mice, suggesting that iron overload promotes oxidative damage to intestinal cells

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10.1080/15548627.2015.1023047 Autophagy 48 HuB.HuS.YangM.LiaoZ.ZhangD.LuoQ.et al (2019)