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IP6-assisted CSN-COP1 competition regulates a CRL4-ETV5 proteolytic checkpoint to safeguard glucose-induced insulin secretion

Gil-Lozano M, Prez-Tilve D, Alvarez-Crespo M, Marts A, Fernandez AM, Catalina PAF, et al

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If you experience persistent side effects, inadequate glucose control, or metabolic plateau at 10 mg, discuss adjustment strategies with your healthcare provider

The long-term safety profile of PT-141 in men is still not clear because there have not been enough big clinical trials presenting clinical evidence