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The ketogenic diet, characterized by low carbohydrates and high fat consumption, has become increasingly popular over the last decade or so

Published research indicates this combination creates a synergistic effect , where the combined receptor activation produces distinct outcomes compared to single-receptor agonism

We're just missing so much more of the conversation

Others require more carbohydrates to fuel intensive training sessions

individual biology is complex and multifactorial

The SURMOUNT-1 trial specifically noted that GI adverse events were the most common reason for treatment discontinuation at higher doses