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72-75 "Palmitoylation of [delta]-catenin by DHHC5 mediates activity-induced synapse plasticity"

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This underdiagnosis can lead, besides death in 20% when it is not appropriately treated, to Korsakoffs syndrome, a severe dysfunction often following untreated Wernickes encephalopathy, that does not remit even with thiamine treatment and is associated with chronic alcohol abuse and chronic thiamine deficiency (5, 6, 11, 28)