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Rakesh Bobba, Consultant Endocrinology & Diabetology at Aster Ramesh Hospitals, shares expert insights on Tirzepatide and Semaglutide injections, two newly approved medications in India that are achieving promising outcomes in obesity management

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By selectively inhibiting NNMT, 5-Amino-1MQ has demonstrated the ability to raise intracellular NAD+ and SAM levels, activate SIRT1, reduce adipocyte differentiation, decrease lipid accumulation, and produce significant fat mass reduction without caloric restriction in preclinical rodent models

Accessed March 11, 2025