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Biochemical assessments of peripheral blood from AD patients demonstrated significantly elevated levels of the mitochondrial fission factor Fis1, with postmortem brain specimens further revealing upregulated Drp1 expression in AD cases (Pakpian et al., 2020)
GO term enrichment was then assessed using the enrichGO function from the ClusterProfiler 30 R package, with the parameter universe set to include all genes detected in the bulk RNA-seq data, minGSSize set to 10, maxGSSize set to 500 and pAdjustMethod set to BH
Additionally, established procedures help support dependable batch-to-batch performance and reliable research material preparation
Clin Immunol Immunopathol (1993) 69:25365
Autoimmune atrophic gastritis--pathogenesis, pathology and management