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2.4 SA--Gal stain SA--Gal staining of cells and tissues was performed using a senescence-associated -galactosidase staining kit (C0602, Beyotime Biotechnology, Shanghai, China), with all procedures strictly following the manufacturers instructions

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Molecular Mechanism: How GHK-Cu Modulates Over 4,000 Human Genes GHK-Cus distinguishing feature is not merely its chelation of copper(II) ions, but its ability to influence transcriptional activity across a broad spectrum of human genes

Moreover, we found that overexpression of GGCT (E98A) mutant significantly reduced cell proliferation compared with overexpression of wild-type GGCT in PC3 and DU145 cells (Fig

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