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Chen K-C, Chung C-H, Lu C-H et al (2020) Association between the use of dipeptidyl peptidase 4 inhibitors and the risk of dementia among patients with type 2 diabetes in Taiwan

Headlines often describe them as miracle drugs, pointing to dramatic weight loss and improvements in blood sugar, heart health and liver disease

Discussion To the best of our knowledge, this is the first head-to-head study evaluating the impact of DPP-4i and GLP-1a on neurocognitive outcomes (i.e., major and mild CI) in older patients with type-2 diabetes, using real-world data

Secondary outcomes included endoscopy use and prescriptions for gastrointestinal medications such as laxatives and prokinetics

doi: 10.1038/s41591-024-03412-w [DOI] [PubMed] [Google Scholar] 50.Manavi MA

Sensitivity Analysis in Observational Research: Introducing the E-Value