2 mg Weeks 14 Introductory dose to establish tolerability
A meta-analysis of 113 RCTs comprising 33,167 patients in the GLP-1 RA cohort and 26,683 in the comparator cohort revealed no significant elevation in pancreatitis or pancreatic cancer risk relative to control groups (Mantel-Haenszel odds ratio [MH-OR] of 0.93 and 0.94, respectively), but identified a notable increase in cholelithiasis risk (MH-OR, 1.30) [58]
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Cluster 1 included allergies, anxiety, depression, chronic obstructive pulmonary disease, fatigue, fever, hypertension, indigestion, insomnia, gastroesophageal reflux disease, hives, swelling, restlessness, and seizures
In the trials, different dosage levels are being tested to see how they impact weight loss and other health markers
How does GLP-1 dosing work for weight loss