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however, CV outcomes trials with these agents showed apparently different treatment effects on CV outcomes

Overall fat mass percentage is also reduced by supplementation and lean body mass is increased

2.3.3 Macrophages BAs attenuate inflammatory responses in gout by suppressing macrophage-mediated inflammation

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Nonfatal myocardial infarction occurred in 2.3% of patients treated with oral semaglutide and 1.9% treated with placebo (HR 1.18, 95% CI 0.731.90), nonfatal stroke occurred in 0.8% versus 1.0% treated with placebo (HR 0.74, 95% CI 0.351.57), and death from cardiovascular causes occurred in 0.9% versus 1.9% treated with placebo (HR 0.51, 95% CI 0.310.84)