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While there have been efforts to improve the drug discovery and development process, traditional approaches still dominate, posing challenges in identifying promising compounds early on and avoiding costly late-stage trials
Glutathione is a naturally occurring antioxidant composed of three amino acids: glycine, cysteine, and glutamic acid
[DOI] [PMC free article] [PubMed] [Google Scholar] 77.Takahashi N, Cho P, Selfors LM, Kuiken HJ, Kaul R, Fujiwara T, et al
Psychoneuroendocrinology (2013) 38:1698708
Oxidative stress can disrupt these tolerance mechanisms by inducing apoptosis of regulatory T cells (Tregs), which are critical for maintaining immune homeostasis and preventing autoimmunity [141]
Besides low serum vitamin B12, elevated methylmalonic acid (MMA) is often seen with B12 deficiency
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