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Yet, individuals with pre-existing conditions may be at increased risk of serious adverse effects (including death) if one considers the possibility that large doses of supplemental vitamin E might interfere with medications, and possibly lower their efficacy or increase their toxicity (1)

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At the body level, kidneys, lungs, and intestines consume most of the circulating GSH [15], highlighting the important oxidative stress that might occur in these organs [1]

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