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TRIUMPH-5 and TRIUMPH-6 TRIUMPH-5 is an active-comparator trial in type 2 diabetes, benchmarking retatrutide against an existing GLP-1 rather than placebo

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Yes, based on vial mass

Current evidence from randomised controlled trials, meta-analyses, and real-world studies indicates no consistent or causal relationship between these agents and serious GI side effects

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However, the exact pharmacokinetic equivalence is not well established for the concentrations typically used in these compounded GLP-1 blends