when it occurs, it is fatal in approximately 50% of cases
GLP-1RAs reduce the expression of cholesterol synthesis and bile acid synthesisassociated genes by inhibiting SREBP-2 in HepG2 cells treated with PA To investigate whether SREBP-2 inhibition mediated by GLP-1RAs affects the expression of cholesterol metabolism-related genes, HepG2 cells were transfected with SREBP-2 siRNA for 24 hours, followed by PA and GLP-1RA treatments
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Itokawa H, Shi Q, Akiyama T, Morris-Natschke SL, Lee KH (2008) Recent advances in the investigation of curcuminoids
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