there are reports that ALA can lower circulating thyroid hormone (T3/T4) or reduce the efficacy of thyroid medications like levothyroxine, which means thyroid function should be monitored if ALA is used concurrently
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Thomas Morley (1558-1602)
Additionally, DSIPs neuroprotective effects suggest it may benefit cognitive health, making it a valuable consideration for individuals seeking to optimize both their sleep and mental performance
However, as we age, our natural glutathione levels decline, making supplementation essential for maintaining optimal health[8]
A 2025 IRB-approved pilot study published in PubMed reported no adverse effects following intravenous administration of 20mg in 2 healthy adults, with monitored biomarkers (heart, liver, kidneys, thyroid, and blood glucose) returning normal results