Management of biochemical recurrence after primary localized therapy for prostate cancer
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JHU-083 markedly suppresses the recruitment of MDSCs by decreasing tumor-derived CSF3 levels via degradation of C/EBP, which in turn increases the numbers of proinflammatory TAMs and enhances antigen presentation to CD8(+) T cells, resulting in stronger T-cell responses 150
Disclaimer : THIS PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY
And three replicates were performed for each treatment
