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Krook-Magnuson and colleagues investigated the impact of on-demand optogenetic stimulation or inhibition of cerebellar Purkinje cells on seizures induced by intrahippocampal kainic acid injections [109]
doi: 10.3390/biom13061004 53
This exceptional BBB permeability stems from its relatively small molecular weight of 750 Da and specific structural modifications that allow passive diffusion across endothelial tight junctions
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Inflammatory Bowel Disease (IBD) and Colitis In models of ulcerative colitis and Crohns-like inflammation, BPC-157 reduced symptoms such as: Intestinal bleeding Epithelial erosion Immune cell infiltration Weight loss and diarrhea BPC-157 therapy improved outcomes in acetic acid-induced colitis models, reducing oxidative stress and promoting mucosal regeneration. Tkalcevic, V
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