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Glucose-dependent insulinotropic polypeptide analogues and their therapeutic potential for the treatment of obesity-diabetes

This does not mean carb cycling, just protein cycling within the ketogenic framework

In the SUSTAIN 8 study, patients with T2DM exhibited a lean mass decrease of 2.3 kg alongside a total weight loss of 5.3 kg, resulting in 43.4% of weight loss attributable to lean mass, while the ratio of lean mass to total mass increased by 1.2% from the baseline [111]

His work helped bring microdosing into public discussion and inspired new research into its possible benefits

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The breadth of the development program reflects confidence in the Phase 2 results and suggests that retatrutide, if approved, will be positioned as a comprehensive metabolic therapy rather than simply a weight loss drug