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Effect on lipid parameters One study demonstrated that following 12 weeks of LC supplementation, participants in the LC group showed significantly increased LC concentrations and enhanced Superoxide dismutase (SOD) activity compared to the placebo group

In the multicenter STEP trial with patients with overweight or obesity and heart failure with preserved ejection fraction (STEP-HFpEF), patients treated with semaglutide 2.4 mg had mean percentage reduction in body weight of 13.3% and experienced significant improvements in heart failure-related symptoms, walking distance, and blood pressure measurements from baseline to 52 weeks [15]

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