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These changes, along with gastrointestinal side effects, may contribute to dry mouth in some users

Many argue that it shouldnt fall under doping classifications

And when GGT stays up, the risk of heart disease, diabetes, and accelerated aging goes up with it

Caution is advised in patients with a history of pancreatitis, and these medications should be avoided during pregnancy or discontinued well before planned conception (e.g., 2 months before planned pregnancy for semaglutide based on its half-life)

The reaction is not driven by enzymes and is dependent on the concentration of sugar in the blood, so it is easy to understand why individuals with diabetes have a greater degree of LDL glycation

& Roden, M