Using the same spot over and over can lead to the buildup of scar tissue (lipohypertrophy), which can impair absorption and make injections more difficult and painful
Pre-Supplementation Medical Evaluation Getting a medical check before starting B12 supplements is a must
For systemic peptides like MOTS-c or SS-31 , the injection site matters less because the peptide enters systemic circulation regardless of where it is administered
The standard 4-6 weeks on, 2-4 weeks off pattern provides a structured approach even without specific data guiding these intervals
In AL amyloidosis, domperidone (up to 20 mg every 6 h before meals) and metoclopramide are recommended [73, 96, 97]
That said, the best day is ultimately the one that fits your lifestyle and allows the most consistent adherence