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Glutathione may interact with certain medications, including chemotherapy drugs and nitroglycerin

from Ayurvedic Supplements A 75-year-old woman in California experienced arsenic poisoning after taking Ayurvedic supplements prescribed to her by a holistic energy healer, according to a report published in July in Clinical Case Reports

Yi Z, Hussain HI, Feng C, Sun D, She F, Rookes JE, Cahill DM, Kong L

It has high biological activity

This does not seem to be the case

However, the studies are generally small, have limited follow-up periods, lack rigorous controls, and not much is known about glutathione dosage for skin whitening