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However, the neuroanatomy of the GLP-1/GLP-1R system in the spinal cord is still poorly understood

GLP-1 drugs slow gastric emptying, which means food and supplements stay in the stomach longer

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The medication is not recommended during second and third trimesters of pregnancy

What You Need Reconstituted retatrutide vial or pen device Appropriate insulin syringe if drawing from a vial (see the retatrutide reconstitution guide for mixing steps) Alcohol swabs Sharps disposal container Optional: gauze or cotton ball for post-injection pressure Site Prep Steps Choose your site for this week from one of the 3 DailyMed-approved zones, rotating from last week's location Clean with an alcohol swab and allow the site to dry for 10 to 15 seconds before injecting (DailyMed label: "Clean the injection site with alcohol before injection") Pinch the skin gently if adequate subcutaneous fat is present, per MSKCC subcutaneous injection guidance Insert the needle at a 45 to 90 degree angle depending on needle length and tissue depth (shorter needles use 90 degrees