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Larger, longer-duration RCTs with standardized biomarker timing and dosing are needed to clarify its clinical relevance

Without adequate vascularization, fibroblasts can't proliferate or synthesize collagen efficientlywhich is why ligaments with poor baseline blood supply (like the ATFL) heal slowly and incompletely

Swallowing peptides means destroying them before they reach the bloodstream

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Discussion: The review underscores the emerging therapeutic strategy of targeting gut microbial modulation