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Although overall structural changes in microbial diversity were not detected, significant shifts in the relative abundance of bacterial taxa were observed in C57BL/6 N mice following 28-day exposure to PET NPs (mean size 56 nm

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For those taking concurrent diabetes medications, dose adjustments may be necessarythe Ozempic SmPC and BNF advise considering reduction of sulfonylurea or insulin doses when initiating GLP-1 receptor agonists to minimise hypoglycaemia risk