Social drivers of health transportation, access to food, socioeconomic status all of that also makes a difference. Cost can often be a prohibitive factor for these medications a months supply of GLP-1 medications can often cost about $1,000 but the analysis included only people who had insurance plans that covered weight-loss medication prescriptions
Future work is recommended to pool multinational datasets to increase precision of estimates, given the low number of suicide and suicide attempt outcomes in the study population
This may explain why fibre consumption is one of the strongest predictors of weight loss and has been shown to enable weight loss even in the absence of calorie restriction
Use stimulant laxatives thoughtfully
Previous analyses have suggested a larger benefit of SGLT-2 inhibitors, as compared with GLP-1RA, on cardiorenal events
[1] While there is no official link established between GLP-1 therapy and magnesium deficiency, the gastrointestinal side effects may theoretically increase the risk of suboptimal magnesium intake or absorption
