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In the SCALE Sleep Apnea RCT, liraglutide 3.0 mg was associated with a significant reduction of apnea-hypopnea index (AHI) compared to placebo (6.1 events per hour, 95% 11 to 1.2 events per hour) at 32 weeks in patients with moderate to severe OSA not on positive airway pressure 20

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Differential effects of the mGluR5 positive allosteric modulator CDPPB in the cortex and striatum following repeated administration

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When a research timeline extends past six weeks, common practice is splitting the reconstituted solution into single-use volumes and freezing them at 20 C immediately