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Aspirin ameliorates immune inflammation in atherosclerosis by modulating the Treg/Th17 axis and CD39-CD73 adenosine signaling through the remodeling of gut microbiota in ApoE / mice 185

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Sham mice were placed in restraint bag and held under impactor for 30 s, then removed from the bag to simulate the stress associated with handling

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Sleep deprivation alters ghrelin and leptin levels (hormones that regulate appetite and digestion), increases cortisol production, and disrupts the circadian rhythm of your gut bacteria