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Moon DO, Kim MO, Choi YH, Hyun JW, Chang WY, Kim GY (2010) Butein induces G(2)/M phase arrest and apoptosis in human hepatoma cancer cells through ROS generation

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Integrins are glycoproteins that play vital roles in cellcell or cellmatrix interactions through heterodimers

The consistency of findings across multiple studies and data sources provides justification of a shift in research focus to conduct well-powered phase 3 randomized controlled trials to validate these preliminary findings and define optimal treatment strategies

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The clinical trial landscape reveals promising avenues for conditions traditionally lacking effective treatments