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GPC3-targeted CAR-T cells secreting B7H3-targeted BiTE exhibit potent cytotoxicity activity against hepatocellular carcinoma cell in the in vitro assay
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However, they also have limitations: many are unstable in the gut, so they are often given by injection, and some have limited human data outside of specific indications
Food Agric 99 , 48494862 (2019)