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The IGF-1 signaling pathway has been implicated in lifespan control across multiple species, and IGF1 LR3 allows for controlled manipulation of this pathway to study its effects on cellular senescence, tissue maintenance, and age-related functional decline

5b) as well as KRAS wild-type models (Extended Data Fig

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Lee J, Pandey AK, Venkatesh S, Thilagavathi J, Honda T, Singh K, et al

Apply 34 drops of the serum to face & neck

This extensive anatomical integration results in substantial overlap between GLP-1 signaling pathways and the mesolimbic dopamine system, which is central to reward-related behaviors