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However, a systematic review in 2023 found only one phase 2 randomized controlled trial of exenatide versus placebo for IIH, which did demonstrate a significant reduction in ICP at all time points, as well as improved headache and visual acuity (7,8)

Researchers suggested that the anti-inflammatory effects of GLP-2 are IL-10-independent and that GLP-2 alters the mucosal response to inflammation through a decrease of lamina propria macrophage TNF- as well as an increase in insulin-like growth factor 1 (IGF-1) production (Ivory et al

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A Renewed Sense of Control Ultimately, combining tirzepatide and B12 isnt about a quick fix